CAS No. 717133-25-0

Chemical Nam           : 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hydrochloride

CAS No                       : 717133-25-0

Molecular Weight       : 378.87

Chemical Formula      : C20H24ClFN2O2

3.1    Classification of the substance or mixture

      GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)

      Sensitisation, skin (Category 1, 1A, 1B ) H317

      Serious eye damage/eye irritation(Category 2A ) H319

                      No Resource File

3.2       GHS Label elements, including precautionary statements:

Pictogram

Signal word Warning

Hazard statement(s)

H317 May cause an allergic skin reaction

H319 Causes serious eye irritation

Precautionary statement(s)

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

2.3 Other hazards: Additional precautionary phrases are located throughout the safety data sheet.

4.1 Description of first aid measures

General advice: Consult a physician. Show this safety data sheet to the doctor in attendance. Move out of dangerous area.

If inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact: Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.

In case of eye contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. Continue rinsing eyes during transport to hospital.

If swallowed: Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed: 

No data available

5.1. Extinguishing media: 

Suitable extinguishing media: alcohol-resistant foam, dry chemical or carbon dioxide

Unsuitable extinguishing media: no data

5.2. Special hazards arising from the substance or mixture: In combustion toxic fumes may form.

5.3. Advice for firefighters: Wear self-contained breathing apparatus.

Wear protective clothing to prevent contact with skin and eyes.

6.1 Personal precautions, protective equipment and emergency procedures

Wear respiratory protection. Avoid dust formation. Avoid breathing vapors, mist or gas.

Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.

Do not attempt to take action without suitable protective clothing.

For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains or river.

Alert the neighborhood to the presence of fumes or gas

6.3 Methods and materials for containment and cleaning up

Mix with sand or vermiculite. Sweep up and shovel. Transfer to a closable, labelled salvage container for disposal by an appropriate method

6.4 Reference to other sections: For disposal see section 13.

7.1 Precautions for safe handling: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Wash hands thoroughly after handling. Ensure there is sufficient ventilation of the area.Normal measures for preventive fire protection. For precautions see section 2.2. 

7.2 Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated area. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Sealed in dry, Ambient Temperature

7.3 Specific end use(s): The end use(s) have not been fully determined. The substance is supplied for Research and Development purposes byprofessionals only.

8.1 Control parameters: 

Components with workplace control parameters: Contains no substances with occupational exposure limit values

8.2 Exposure controls:

Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

Personal protective equipment:

Eye/face protection: Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove’s outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

Body Protection: Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Control of environmental exposure: Do not let product enter drains.

1. a) Appearance Powder  
2. b) Odour Off-White to White color powder
3. c) Odour No data available
4. d) pH No data available
5. e) Melting point/freezing point No data available
6. f) Initial boiling point and boiling range No data available

1. g) Flash point No data available
2. h) Evaporation rate No data available
3. i) Flammability (solid, gas) No data available
4. j) Upper/lower flammability or explosive limits No data available
5. k) Vapour pressure No data available
6. l) Vapour density No data available
7. m) Relative density No data available
8. n) Water solubility No data available
9. o) Partition coefficient: n-octanol/water No data available
10. p) Auto-ignition temperature No data available
11. q) Decomposition temperature No data available
12. r) Viscosity No data available
13. s) Explosive properties No data available
14. t) Oxidizing properties No data available

9.2. Other safety information:

No data available

10.1 Reactivity: No data available

10.2 Chemical stability: Stable under recommended storage conditions. 

10.3 Possibility of hazardous reactions: No data available

10.4 Conditions to avoid: Not data available

10.5 Incompatible materials: Not data available

10.6 Hazardous decomposition products: 

Carbon monoxide , carbon dioxide , hydrogen chloride , hydrogen fluoride , nitrogen oxides

Carcinogenicity:  IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.

Not available.

Disposal Operations: Consult state, local or national regulations for proper disposal. Hand over to authorized disposal company as hazardous waste. 

Disposal of Packaging: Disposal must be made according to official regulations.

Not data available.

Safety, health and environmental and national regulations: Product is not subject to any additional regulations or provisions

Safety Assessment: No Chemical Safety Assessment

The information above is believed to be accurate and represents the best information currently available to us.