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Compound Information

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Structure

Product Name

3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-
2(1H)-one
(CAS No. 536760-29-9)

CAS No.

536760-29-9

PropertyDetails
Product Name3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-
2(1H)-one
(CAS No. 536760-29-9)
Structure
CAS No.CAS No. 536760-29-9
Related to PharmaApixaban
Molecular FormulaC 11 H 9 ClN 2 O 3
Formula Weight252.65
Storage ConditionAmbient

Compound Specification

PropertyDetails
DescriptionWhite to off white powder
Identification by HPLCThe RT of the Major peak in the chromatogram of the
test sample should correspond to that of working
standard.
Chromatographic purity by HPLC (% in area normalization)
PurityNot less than 99.0%

SDS Information

Product Identification

Chemical Name : 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
CAS No : 536760-29-9
Molecular Weight : 252.7
Chemical Formula : C11H9ClN2O3

Composition/Information on Ingredients

IngredientCAS NoClassificationConcentration
3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one

536760-29-9

H302≤ 100

Hazards Identification

3.1 Classification of the substance or mixture: GHS Classification in accordance with 29 CFR
1910 (OSHA HCS) Acute toxicity,oral (Category 4), H302
3.2. GHS Label elements, including precautionary statements:
Hazard statement(s): H302 Harmful if swallowed
Precautionary statement(s):
P264 : Wash thoroughly after handling.
P270 : Do not eat, drink or smoke when using this product.
P301+P312+P330 : If swallowed: Call a POISON CENTER or doctor/physician if you feel unwell.

Rinse mouth.

P501 : Dispose of contents/container to an approved waste disposal plant.

First Aid Measures Eyes

4.1. Description of first aid measures:
General advice: Consult a physician. Show this safety data sheet to the doctor in

attendance. Move out of dangerous area.

If inhaled: Remove victim to fresh air. In severe cases or if symptoms persist, seek medical

attention.

In case of skin contact: Immediately wash skin with copious amounts of water for at least
15 minutes while removing contaminated clothing and shoes. If irritation
persists, seek medical attention.

In case of eye contact: Immediately flush with plenty of water. After initial flushing,
remove any contact lenses and continue flushing for at least 15 minutes.
Keep eye wide open while rinsing. Get medical attention.

If swallowed: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse

mouth.

4.2. Most important symptoms and effects, both acute and delayed: See Section 2.2 or in Section 11.
4.3. Indication of any immediate medical attention and special treatment needed: No data

Fire Fighting Measures

5.1. Extinguishing media: Use dry sand, dry chemical or alcohol-resistant foam for extinction.
5.2. Special hazards arising from the substance or mixture: Carbon monoxide, nitrogen oxides,

hydrogen chloride.

5.3. Advice for firefighters: Wear self-contained breathing apparatus for firefighting if necessary.

Accidental Release Measures

6.1. Personal precautions, protective equipment and emergency procedures: Ensure adequate
ventilation. Use personal protective equipment.
6.2. Environmental precautions: Should not be released into the environment. See Section 12 for
additional ecological information.
6.3. Methods and materials for containment and cleaning up: Sweep up or vacuum up spillage and
collect in suitable container for disposal.
6.4. Reference to other sections: Refer to protective measures listed in Sections 8 and 13

Handling and Storage

7.1. Precautions for safe handling: Avoid contact with skin and eyes. Avoid inhalation of vapour or
mist. Keep away from sources of ignition – No smoking. Take measures to prevent the build up of
electrostatic charge. For precautions see section 2.2.
7.2. Conditions for safe storage, including any incompatibilities: Store Ambient. Keep container
tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully
resealed and kept upright to prevent leakage.
7.3. Specific end use(s): Laboratory chemicals, for scientific research and development only.

Exposure Controls/Personal Protection

8.1. Control parameters:
Components with workplace control parameters: Contains no substances with occupational
exposure limit values.

8.2. Exposure controls:
Appropriate engineering controls: Ensure that eyewash stations and safety showers are close
to the workstation location. Ensure adequate ventilation, especially in confined areas.
Personal protective equipment:
Eye/face protection: Wear appropriate protective eyeglasses or chemical safety goggles as
described by OSHA’s eye and face protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin protection: Handle with gloves. Gloves must be inspected prior to use. Use proper glove
removal technique (without touching glove’s outer surface) to avoid skin contact with this
product. Dispose of contaminated gloves after use in accordance with applicable laws and good
laboratory practices. Wash and dry hands
Body Protection: Complete suit protecting against chemicals, Flame retardant antistatic
protective clothing., The type of protective equipment must be selected according to the
concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection: No protective equipment is needed under normal use conditions.
Control of environmental exposure: Prevent further leakage or spillage if safe to do so. Do not
let product enter drains.

Physical and Chemical Properties

9.1. Information on basic physical and chemical properties
(a) Appearance: White to off white powder
(b) Odour: No data
(c) Odour Threshold: No data
(d) pH: No data

(e) Melting point/freezing point: 170 – 180◦C

(f) Initial boiling point and boiling range: No data
(g) Flash point: No data
(h) Evaporatoin rate: No data
(i) Flammability (solid, gas): No data
(j) Upper/lower flammability or explosive limits: No data
(k) Vapour pressure: No data
(l) Vapour density: No data
(m) Relative density: No data
(n) Water solubility: No data
(o) Partition coefficient: n-octanol/water: No data
(p) Auto-ignition: No data
(q) Decomposition temperature: No data
(r) Viscosity: No data
(s) Explosive properties: No data
(t) Oxidizing properties: No data
9.2. Other safety information:
Formula : C11H9ClN2O3
Molecular weight : 252.7
CAS Number : 536760-29-9

Stability and Reactivity

10.1. Reactivity No data
10.2. Chemical stability Stable under recommended storage conditions.
10.3. Possibility of hazardous reactions No data
10.4. Conditions to avoid
10.5. Incompatible material No data.

10.6. Hazardous decomposition products:

Hazardous decomposition products formed under fire conditions: Carbon monoxide, nitrogen oxides,
hydrogen chloride. Other decomposition products: No data In the event of fire: See Section5

Toxicological Information

11.1 Information on toxicological effects
Acute toxicity: Harmful if swallowed.
Skin irritation/corrosion: No data available.
Eye damage/irritation: No data available.
Respiratory or skin sensitization: No data available.
Germ cell mutagenicity: No data available.
Carcinogenicity: No data available.
Reproductive toxicity: No data available.
Specific target organ system toxicity – single exposure: No data available.
Specific target organ system toxicity – repeated exposure: No data available.
Aspiration hazard: No data available.
Additional information: To the best of our knowledge, the chemical, physical and toxicological
properties of this substance have not been thoroughly investigated.

Ecological Information

Not available.

Disposal Considerations

13.1. Waste treatment methods

Product : Arrange disposal as special waste, by licensed disposal
company, in consultation with local waste disposal authority, in accordance with national and
regional regulations.
Contaminated packaging: Dispose of as unused product.

Transport Information

No data available

Regulatory Information

No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.

Other Information

The information above is believed to be accurate and represents the best information currently
available to us.