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Compound Information

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Structure

Product Name

N-(4-Fluorobenzyl)-1-Methyl-4-PiperidinAmine (CAS No. 359878-47-0)

CAS No.

359878-47-0

PropertyDetails
Product Name

N-(4-Fluorobenzyl)-1-Methyl-4-PiperidinAmine (CAS No. 359878-47-0)

Structure
CAS No.359878-47-0
Related to PharmaPimavanserin
Molecular FormulaC 13 H 19 FN 2
Formula Weight223.31
Storage ConditionAmbient

Compound Specification

PropertyDetails
DescriptionA color less to yellow color liquid
Identification by HPLCThe Retention time of the major peak in the
Chromatogram of test solution should correspond to
that in the chromatogram of standard solution, as
obtained in the related compounds by HPLC method
 
PurityNot less than 99.0%

SDS Information

Product Identification

Chemical Name : N-[(4-Fluorophenyl)methyl]-1-methyl-4-piperidinamine
CAS No : 359878-47-0
Molecular Weight : 222.3
Chemical Formula : C₁₃H₁₉FN₂

Composition/Information on Ingredients

IngredientCAS NoClassificationConcentration

N-[(4-Fluorophenyl)methyl]-1-methyl-4-piperidinamine

359878-47-0

 —

Hazards Identification

Classification of the substance or mixture
GHS Hazards Classification (According to EU Regulation 1272/2008 and US OSHA 1910.1200)
Acute Toxicity, Oral (Category 4)
Skin Irritation (Category 2)
Eye Damage/Irritation (Category 2A)
Specific Target Organ Toxicity, Single Exposure; Respiratory Tract Irritation (Category 3)
GHS Hazards Identification (According to EU Regulation 1272/2008 and US OSHA 1910.1200)
Pictogram

Signal word: Warning
Hazard statement(s)
H302 Harmful if swallowed.
H315 Causes skin irritation.

SDS Information

H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
Precautionary statement(s)
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264 Wash hands thoroughly after handling.
P301/P312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel
unwell.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray
P302/P352 IF ON SKIN: Wash with plenty of soap and water
P305/P351/P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

First Aid Measures Eyes

4.1 Description of first aid measures
General Advice: If medical attention is required, show this safety data sheet to the doctor.
If Inhaled: If inhaled, move person to fresh air. If not breathing, give artificial respiration and
consult a physician.
In Case of Skin Contact: Wash affected area with soap and water. Consult a physician if any
exposure symptoms are observed.
In Case of Eye Contact: Immediately rinse eyes with plenty of water for at least 15 minutes.
Consult a physician.
If Swallowed: Never give anything by mouth to an unconscious person. Rinse mouth with water.
Do NOT induce vomiting unless advised to do so by a physician or Poison Control Center. Seek
medical attention.

4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labeling (see section
2.2) and/or section 11.
4.3 Indication of any immediate medical attention and special treatment needed
No data available

Fire Fighting Measures

5.1 Extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides, Hydrogen fluoride
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary. Use personal protection
equipment.

Accidental Release Measures

Personal precautions: Wear respiratory protection. Avoid dust formation. Avoid breathing vapours,
mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
Avoid contact with skin, eyes or clothing.
Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product
enter drains.
Method and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal.

Handling and Storage

7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.

7.2 Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place.
Keep in a dry place.
Storage conditions: Ambient
7.3 Specific end use(s)
For scientific research and development only. Not for use in humans or animals.

Exposure Controls/Personal Protection

8.1 Control parameters: Contains no components with established occupational exposure limits.
8.2 Exposure controls
Appropriate engineering controls
A laboratory fume hood or other appropriate form of local exhaust ventilation should be used to avoid
exposure.
Personal protective equipment: All recommendations below are advisory in nature and a risk assessment should be performed by the employer/end user prior to use of this product. The type of protective equipment must be selected based on the amount and concentration of the dangerous material being used in the workplace.
Eye/face protection: Safety goggles or face shield. All equipment should have been tested and approved under appropriate standards, such as NIOSH (US), CSA (Canada), or EN 166 (EU).
Skin protection: Gloves should be used when handling this material. Gloves are to be inspected prior to use. Contaminated gloves are to be removed using proper glove removal technique so that the outer
surface of the glove does not contact bare skin. Dispose of contaminated gloves after use in compliance with good laboratory practices and local requirements. Gloves used for incidental
exposures (splash protection) should be designated as “chemical resistant” by EU standard EN 374 with the resistance codes corresponding to the anticipated use of the material. Unrated gloves are not recommended.
Suggested gloves: AnsellPro Sol-Vex nitrile gloves style 37-175, 15 mil thickness.

Penetration time has not been determined. Gloves used for prolonged direct
exposure (immersion) should be designated “chemical resistant” as per EN 734 with the resistance

codes corresponding to the anticipated use of the material.
Suggested gloves: ImpelPro Viton/Butyl gloves style 38-612, 4/8 mil thickness.
Penetration time has not been determined. These recommendations may not apply if the material is
mixed with any other chemical, or dissolved into a solution. A risk assessment must be performed to
ensure the gloves will still offer acceptable protection.
Body Protection: Fire resistant (Nomex) lab coat or coveralls.
Respiratory protection: Recommended respirators are NIOSH-approved N100 or CEN-approved
FFP3 particulate respirators. These are to be only used as a backup to local exhaust ventilation or
other engineering controls. If the respirator is the only means of protection, a full-face supplied air
respirator must be used.

Physical and Chemical Properties

PHYSICAL AND CHEMICAL PROPERTIES
Appearance A color less to yellow color liquid
Boiling Point No data available
Melting Point No data available
Odour No data available
Odour Threshold No data available
pH No data available
Flash point No data available
Evapouration rate No data available
Vapour pressure No data available
Vapor Density No data available
Relative density No data available
Solubility in water No data available
Auto-ignition temperature No data available
Decomposition temperature No data available

Viscosity No Data No data available

Explosive properties No data available

Stability and Reactivity

10.1 Reactivity: No data available
10.2 Chemical stability: Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions: No data available
10.4 Conditions to avoid: Not data available
10.5 Incompatible materials: Strong oxidizing agents
10.6 Hazardous decomposition products: Not data available

Toxicological Information

No data available

Ecological Information

Not available.

Disposal Considerations

Product: Product may be burned in an incinerator equipped with afterburner and scrubber. Excess
and expired materials are to be offered to a licensed hazardous material disposal company. Ensure
that all Federal and Local regulations regarding the disposal and destruction of this material are
followed.
Contaminated Packaging: Dispose of as above.
Other Considerations: Product is not to be disposed of in sanitary sewers, storm sewers, or
landfills.

Transport Information

Not available.

Regulatory Information

A) Canada
DSL/NDSL Status: This product is not listed on the Canadian DSL/NDSL
B) United States

TSCA Status: This product is not listed on the US EPA TSCA.

C) European Union
ECHA Status: This product is not registered with the EU ECHA.

Other Information

The information above is believed to be accurate and represents the best information currently available to us.